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ENVARSUS XR Savings and Support

We are committed to helping patients with kidney transplants in many different ways. When your doctor chooses ENVARSUS XR for you, it’s important that you are able to obtain it from the pharmacy and afford it. We offer ENVARSUS XR savings programs that can help patients with all different types of insurance. If you need help figuring out how and where to get prescriptions, we have a dedicated team that is ready and available to help you.

Learn how patients with insurance coverage can save on ENVARSUS XR

Pay as little as $0 for ENVARSUS XR*

Eligible patients with commercial insurance may be eligible for the $0 Co-pay Card.

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Sign Up for $0 Co-pay Card

By checking this box and using this co-pay card, I acknowledge that I currently meet the Eligibility Criteria and agree to comply with the Terms and Conditions described here. If I am the parent or legal guardian of a 17-year-old patient completing this attestation on behalf of the patient, I acknowledge that the patient currently meets the Eligibility Criteria and agrees to comply with the Terms and Conditions described here.
By checking this box, I acknowledge that Veloxis, or companies acting on its behalf, may send me (or the patient) materials about other offers, use my (or the patient’s) information to develop or improve products and services, or contact me (or the patient) in the future about health-related topics or market research.
By checking this box, I certify that I am a renal transplant recipient eligible to participate in this program, and I understand and agree to comply with the Program Terms, Conditions, and Eligibility Criteria. If I am the parent or legal guardian of a 17-year-old patient and I am completing this attestation on behalf of the patient, I acknowledge that the patient currently meets the Eligibility Criteria and agrees to comply with the Terms and Conditions.
By checking this box, I certify that I am 17 years of age or older. If I am the parent or legal guardian of a patient and am completing this attestation on behalf of the patient, I certify that the patient is 17 years of age or older.
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Enroll in Veloxis Transplant Support

A dedicated Veloxis Transplant Support specialist is waiting to help you with finding savings, getting coverage, and filling your ENVARSUS XR prescription. You can reach Veloxis Transplant Support at 1-844-Veloxis (1-844-835-6947).

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Benefit investigation
Verifies your insurance coverage and identifies possible restrictions.

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Prior authorization assistance
Guides you through every step of your insurer's process, including identifying prior authorization requirements.

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Alternative funding research
Identifies independent groups that can assist patients who are uninsured or underinsured.

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Patient Assistance Program
Provides free ENVARSUS XR for eligible patients who meet certain criteria.

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Coordination with specialty pharmacies
ENVARSUS XR is available from most major pharmacies and is available from all of the largest pharmacy wholesalers. We can help connect you with a pharmacy that has ENVARSUS XR in stock or a specialty mail-order pharmacy to deliver ENVARSUS XR refills to your door.



*Eligible insured patients can save up to a maximum benefit of $8550 annually off the patient’s co-pay or out-of-pocket expenses of ENVARSUS XR. Patient is responsible for any differential over $8550. Offer not valid for cash-paying patients or where drug is not covered by the primary insurance. This offer is valid in the United States. No substitutions permitted. Offer not valid for prescriptions reimbursed under Medicaid, a Medicare drug benefit plan, TRICARE, or other federal or state health programs (such as medical assistance programs).

Please tell us more about you:

I am expecting a kidney transplant (or am a family member/caregiver) ▶
I am an ENVARSUS XR patient (or am a family member/caregiver) ▶
I have had a kidney transplant and am not currently on ENVARSUS XR (or am a family member/caregiver) ▶
I am a healthcare professional ▶
Other ▶

What are you interested in learning about?

General information about immunosuppression ▶
Information about ENVARSUS XR ▶
Hear a transplant patient’s story ▶
General transplant resources and education ▶
Visit “About Immunosuppression” ▶
Visit “Why ENVARSUS XR?” ▶
Visit “Resources” ▶
Visit “Resources” ▶
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IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENVARSUS XR?

ENVARSUS XR can cause serious side effects, including:

Increased risk of cancer. People who take ENVARSUS XR have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma).

Increased risk of infection. ENVARSUS XR is a medicine that affects your immune system. ENVARSUS XR can lower the ability of your immune system to fight infections. Serious infections can happen in people receiving ENVARSUS XR that can cause death.

Call your healthcare provider right away if you have symptoms of an infection such as:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENVARSUS XR?

ENVARSUS XR can cause serious side effects, including:

Increased risk of cancer. People who take ENVARSUS XR have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma).

Increased risk of infection. ENVARSUS XR is a medicine that affects your immune system. ENVARSUS XR can lower the ability of your immune system to fight infections. Serious infections can happen in people receiving ENVARSUS XR that can cause death.

Call your healthcare provider right away if you have symptoms of an infection such as:

  • fever
  • cough or flu-like symptoms
  • warm, red, or painful areas on your skin
  • sweats or chills
  • muscle aches

What is ENVARSUS XR?

ENVARSUS XR is a prescription medicine used with other medicines to help prevent organ rejection in people who have had a kidney transplant.

ENVARSUS XR is an extended-release tablet and is not the same as tacrolimus extended-release capsules, tacrolimus immediate-release capsules or tacrolimus for oral suspension. Your healthcare provider should decide what medicine is right for you.

Who should not take ENVARSUS XR?

Do not take ENVARSUS XR if you are allergic to tacrolimus or any of the ingredients in ENVARSUS XR.

What should I tell my healthcare provider before taking ENVARSUS XR?

Before you take ENVARSUS XR, tell your healthcare provider if you:

  • plan to receive any live vaccines. Ask your healthcare provider if you are not sure if your vaccine is a live vaccine.
  • have or have had liver, kidney or heart problems.
  • have any other medical conditions.
  • are pregnant or plan to become pregnant. ENVARSUS XR may harm your unborn baby.
    • If you are able to become pregnant, you should use effective birth control before and during treatment with ENVARSUS XR. Talk to your healthcare provider about birth control methods that may be right for you.
    • Males who have female partners that are able to become pregnant should also use effective birth control before and during treatment with ENVARSUS XR. Talk to your healthcare provider before starting treatment with ENVARSUS XR about birth control methods that may be right for you.
    • There is a pregnancy registry for females who become pregnant and males who have fathered a pregnancy during treatment with ENVARSUS XR. The purpose of this registry is to collect information about your health and of your baby. To enroll in this voluntary registry, call 1-877-955-6877.
  • are breastfeeding or plan to breastfeed. ENVARSUS XR passes into your breast milk. You and your healthcare provider should decide if you will breastfeed while taking ENVARSUS XR.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, natural, herbal or nutritional supplements.

ENVARSUS XR may affect the way other medicines work, and other medicines may affect how ENVARSUS XR works.

How should I take ENVARSUS XR?

Take ENVARSUS XR exactly as your healthcare provider tells you to take it.

Your healthcare provider may change your dose of ENVARSUS XR if needed. Do not stop taking or change your dose of ENVARSUS XR without talking to your healthcare provider.

Take ENVARSUS XR once daily with fluid (preferably water) on an empty stomach, at least 1 hour before or at least 2 hours after a meal, at the same time each day (preferably in the morning).

Take ENVARSUS XR tablets whole. Do not chew, divide, crush, or dissolve ENVARSUS XR tablets before swallowing. If you cannot swallow ENVARSUS XR tablets whole, tell your healthcare provider.

If you miss your dose of ENVARSUS XR, it should be taken as soon as possible, but no longer than 15 hours after missing your dose. If the time after you miss your dose is more than 15 hours, the missed dose should be skipped and the next dose should be taken the following morning at your regularly scheduled time. Do not take 2 doses at the same time.

If you take too much ENVARSUS XR, call your healthcare provider or go to the nearest hospital emergency room right away.

What should I avoid while taking ENVARSUS XR?

Live vaccines such as flu vaccine through your nose, measles, mumps, rubella, polio by mouth, BCG (TB vaccine), yellow fever, chicken pox (varicella), or typhoid.

Exposure to sunlight and UV light such as tanning machines. Wear protective clothing and use a sunscreen.

You should not eat grapefruit or drink grapefruit juice while taking ENVARSUS XR.

You should not drink alcohol while taking ENVARSUS XR.

What are the possible side effects of ENVARSUS XR?

ENVARSUS XR may cause serious side effects, including:

See “What is the most important information I should know about ENVARSUS XR?”

Problems from medication errors such as graft rejection and other serious reactions. People who take ENVARSUS XR have sometimes been given the wrong medicine because some medicines have the same ingredient (tacrolimus) as ENVARSUS XR. Check your ENVARSUS XR when you get a new prescription to make sure you have received the right medicine.

  • Call your healthcare provider right away if you think you were given the wrong medicine.
  • Ask your healthcare provider or pharmacist if you are not sure what ENVARSUS XR should look like.

High blood sugar (diabetes). Your healthcare provider may do certain tests to check for diabetes while you take ENVARSUS XR. Call your healthcare provider right away if you have:

  • frequent urination
  • confusion
  • fruity smell on your breath
  • increased thirst or hunger
  • drowsiness
  • nausea, vomiting, or stomach pain
  • blurred vision
  • loss of appetite

Kidney problems. Kidney problems are serious and common side effects of ENVARSUS XR. Your healthcare provider may do certain tests to check for kidney function while you take ENVARSUS XR.

Nervous system problems. Nervous system problems are a serious and common side effect of ENVARSUS XR. Call your healthcare provider right away if you get any of these symptoms while taking ENVARSUS XR. These could be signs of serious nervous system problems:

  • confusion
  • numbness and tingling
  • vision changes
  • coma
  • headache
  • muscle tremors
  • seizures

High levels of potassium in your blood. Your healthcare provider may do certain tests to check your potassium level while you take ENVARSUS XR.

High blood pressure. Your healthcare provider will monitor your blood pressure while you take ENVARSUS XR.

Changes in the electrical activity of your heart (QT prolongation).

Severe low blood cell count (anemia)

The most common side effects of ENVARSUS XR are, diarrhea, urinary tract infection, low red blood cell count (anemia), high blood pressure, and constipation.

These are not all the possible side effects of ENVARSUS XR. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store ENVARSUS XR?

Store ENVARSUS XR at room temperature between 68° F to 77° F (20° C to 25° C).

Safely throw away medicine that is out of date or no longer needed.

Keep ENVARSUS XR and all medicines out of reach of children.

General information about the safe and effective use of ENVARSUS XR.

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use ENVARSUS XR for a condition for which it was not prescribed. Do not give ENVARSUS XR to other people, even if they have the same symptoms that you have. It may harm them.

This Medication Guide summarizes the most important information about ENVARSUS XR. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about ENVARSUS XR that is written for health professionals. For more information, go to www.ENVARSUSXR.com or call 1-844-Veloxis (1-844-835-6947).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see the accompanying Medication Guide and full Prescribing Information, including Boxed Warning (PDF).